Brushite-Forming Mg-, Zn- and Sr-Substituted Bone Cements for Clinical Applications
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چکیده
منابع مشابه
Brushite-Forming Mg-, Zn- and Sr-Substituted Bone Cements for Clinical Applications
Calcium phosphate cements have been in clinical use for the last 10 years. Their most salient features include good biocompatibility, excellent bioactivity, self-setting characteristics, low setting temperature, adequate stiffness, and easy shaping to accomodate any complicated geometry. They are commonly used in filling bone defects and trauma surgeries as mouldable paste-like bone substitute ...
متن کاملMagnesium substitution in brushite cements for enhanced bone tissue regeneration.
We have synthesized calcium phosphate cements doped with different amounts of magnesium (Mg-CPC) with a twofold purpose: i) to evaluate in vitro the osteoblast cell response to this material, and ii) to compare the bone regeneration capacity of the doped material with a calcium cement prepared without magnesium (CPC). Cell proliferation and in vivo response increased in the Mg-CPCs in compariso...
متن کاملSr-substituted bone cements direct mesenchymal stem cells, osteoblasts and osteoclasts fate
Strontium-substituted apatitic bone cements enriched with sodium alginate were developed as a potential modulator of bone cells fate. The biological impact of the bone cement were investigated in vitro through the study of the effect of the nanostructured apatitic composition and the doping of strontium on mesenchymal stem cells, pre-osteoblasts and osteoclasts behaviours. Up to 14 days of cult...
متن کاملDicalcium phosphate cements: brushite and monetite.
Dicalcium phosphate cements were developed two decades ago and ever since there has been a substantial growth in research into improving their properties in order to satisfy the requirements needed for several clinical applications. The present paper presents an overview of the rapidly expanding research field of the two main dicalcium phosphate bioceramics: brushite and monetite. This review b...
متن کاملNovel Osteointegrative Sr-Substituted Apatitic Cements Enriched with Alginate
The present work describes the synthesis of novel injectable, self-setting bone cements made of strontium-substituted hydroxyapatite (Sr-HA), obtained by single-phase calcium phosphate precursors doped with different amounts of strontium and enriched with alginate. The addition of alginate improved the injectability, cohesion, and compression strength of the cements, without affecting the harde...
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ژورنال
عنوان ژورنال: Materials
سال: 2010
ISSN: 1996-1944
DOI: 10.3390/ma3010519